Do the prescription drugs Nexium and AcipHex have the same treatment results?
As a general rule, standard doses of proton pump inhibitors (20 mg of omeprazole, 30 mg of lansoprazole, 20 mg of rabeprazole, or 40 mg of pantoprazole, all administered before breakfast) will relieve symptoms and heal esophagitis in approximately 85 to 90 percent of patients.Most patients with GERD, particularly those with sever esophagitis, will relapse once therapy is discontinued.AcipHex possesses a slightly faster onset of action because of its pharmacokinetics. Overall, when comparing proton pump inhibitors (PPI), such as Nexium and AcipHex, while some differences have been reported, the magnitude of differences has been small and of uncertain clinical importance. In particular, the degree to which any of the reported differences would justify the selection of one versus another PPI, particularly when considering cost-effectiveness, is unclear.-physician at large.
